Two form sides meet at St James’ Park looking for a place in the last eight of the EFL Cup.
The Lilywhites go into the game seven games unbeaten in all competitions, whilst the home side are in the same boat, seven unbeaten, winning their last five games.
But something must give on Tyneside and only one team can progress to the last eight of the cup, with North End aiming to make it to that stage of the competition for the first time in their history.
In the last round manager Simon Grayson made ten changes as his side overcame AFC Bournemouth at the Vitality Stadium.
He will definitely be without Saturday’s match winner Alex Baptiste and Marnick Vermijl who are both cup tied, even though the latter is now fully recovered from his hamstring injury.
However, hat-trick hero against the Cherries, Simon Makienok, could well be given another chance and Jermaine Beckford should have his first involvement since August after two full weeks back in training following his own hamstring injury.
Aiden McGeady (hamstring), John Welsh (calf) and long term casualty Calum Woods (knee) are all ruled out, whilst Stevie May continues to join in with full training after almost a year on the sidelines.
In the last round Rafa Bentiez also made changes, but not on the scale of his opposite number, but with a trip to Deepdale at the weekend, the Spaniard could well make alterations to his line-up for the visit of the Lilywhites with a number of his key players given a rest.
The Match Official
For the second time this season the Lilywhites will be officiated by Andy Madley on Tuesday night, the man who took charge of our Play-Off Final in 2015.
In 2014/15, he took charge of three North End games, including the win at Wembley, having been the man with the whistle in the first league win of the season, the 4-0 triumph at Scunthorpe United back in August of 2014 and then the live game against Fleetwood Town at Highbury in March 2015, which ended 1-1.
If you think the name rings a bell, it should. Mr Madley was also in charge of our now memorable Cup win over Blackpool in 2013/14 and then also took charge at Port Vale when North End won 2-0 with ten men.
Before Loftus Road, the last time Mr Madley took charge of a PNE game was in last season's 1-0 win over MK Dons at stadium:mk on 15th August 2015.
Tickets are on sale for the tie until 2pm on the day of the game and by calling 0344 856 1966, in person from the ticket office or online 24/7 at MyPNE.Com until 12 noon.
We have been given an initial allocation of 1,112 and tickets are only available in advance – you cannot buy on the night at St James’ Park and supporters are asked not to travel without a ticket.
Ticket prices are £10 for adults and £3 for concessions. All supporters under the age of 12 must be accompanied by an adult. Fans will be asked to prove their age and those under the age of 12 who cannot identify a chaperone may be denied entry to the game.
There are four pairs of wheelchair and carer tickets priced at £5 with the carer ticket free of charge. Ambulant disabled tickets are taken from the main allocation and are also priced at £5 with the carer ticket free of charge.
There are a limited amount of disabled parking bays available which are free of charge and can be booked by calling 0191 2018666 on the week of the game.
Coach travel is also available for this fixture and is priced at £15 for all. Coaches will depart both Deepdale and Leyland at 3.15pm.
If you can’t get to St James’ Park, Anthony Wareing will be live on PNE Player from 7.15pm bringing you live and uninterrupted match commentary and he will have Paul McKenna alongside him.
You can also follow the game on our official Twitter feed @pnefc, and online at facebook.com/officialPNEFC. Whilst from midnight on Wednesday highlights of the game will be available, both in extended version on PNE Player HD and a shortened 90 second version on our YouTube site youtube.com/pnefcofficial.
To watch what assistant manager Glynn Snodin has to say about the game, click below
To hear from Simon Makienok when he spoke to PNE PlayerHD to preview the clash click below