The Lilywhites, who have already tasted success at their neighbours with a 2-1 victory in League One earlier this season, will travel to play Kevin Blackwell’s side the week commencing 3rd December.
North End’s route to the third round has seen them overcome Carlisle United on penalties and a superb fight back from 1-0 down to beat Morecambe 4-2 at the Globe Arena.
Ticket details will be announced here first on PNE.Com as Graham Westley’s men continue on the road towards Wembley.
The ticket office is open for business as usual today ahead of Sunday's clash against MK Dons, so if you haven't yet got your ticket then this is your chance now.