North End manager Simon Grayson believes it could be a once in a lifetime experience for some of his players when Manchester United come to town on Monday evening.
"We've got a fantastic game on Monday night, fantastic for the football Club and fantastic for the supporters that we're goign to be able to ply our trade against some of the best players, not only in the Premier League, but in world football.
" Obviously the manager has been there and done it at so many different clubs, won so much silverwear, it's just a fantastic tie for us to be involved in.
"This is what you work so hard for, these games. The players work hard pre-season and over the course of the season to try and get the opportunity to go and play against the best players. Most notably against players that probably our players will never get the chance to maybe play against again.
"That's no disrespect, our players are in League One for a reason and potentially some might go into the Premier League one day but these players are gracing World Cups, the finest stadiums and games around the globe.
"It will be an unbelievable experience for the players, you don't realise actually how big a tie this is when you see it until you realise the number of TV stations and how many countries it's going to hit over the next few days.
"It's going to be a fantastic atmosphere, there's going to be so much media, publicity for everybody and we've just got to go and embrace it and see where it takes us. It will be a special atmosphere and obviously we just ask everybody to give it their all both on the pitch and off it to make a good atmosphere and a positive place to be."
To hear more from Simon Grayson on the upcoming FA Cup tie, team selection and more go to PNE Player for the extended interview.