The reward for beating Premier League Bournemouth in the third round of the EFL Cup is a tie against Rafa Benitez's Newcastle United in the last 16 for PNE.
The draw was made live on Sky Sports by Phil Thompson and Matt Murray after Manchester United had defeated Northampton Town to become one of those last 16 teams in the competition.
The Lilywhites earned the chance to play for a quarter-final place by coming from 2-1 down to defeat the Cherries at the Vitality Stadium courtesy of a hat-trick from Danish striker Simon Makienok.
The last 16 tie will be played week commencing the 24th October, and full details will be available on PNE.Com from later this week.