North End were in the home run on their way to the Play-Off Final at the Millennium Stadium when they headed to Millmoor to face Rotherham United over Easter 2005.
And it was the Lilywhites who came out on top as Chris Sedgwick scored against his former club to start a second half comeback and keep the team on track for a place in the top six, that would ultimately end in the clash with West Ham United.
Will Hoskins had given the Millers the lead from 25 yards with an attempted cross that finished in the North End goal past Carlo Nash.
But Sedgwick converted Richard Cresswell's though ball after the break with a 20-yard strike to rouse the boisterous following supporter who had headed in numbers across the Pennines.
And then Youl Mawene hooked the ball past scored Mike Pollitt for the winner to send the fans into raptures, with David Nugent almost adding a third late on, only to strike the woodwork with a shot from the edge of the box.
After the game, United boss Mick Harford said: "I want to be successful and I want Rotherham United to be successful, but now we need to get ready for next season.
"We need to have a squad capable of challenging for promotion and we know we will need a strong squad. But I cannot fault the players on their effort against Preston."
Whilst then PNE manager Billy Davies added: "We were sluggish in the first half, but the second half was okay. This was a very difficult game for us and all credit to the players for their commitment in the second half.
"The home fans were great to Chris Sedgwick on his return to Rotherham and it was a great finish by him for our first goal."
Rotherham United line-up: Pollitt, Scott (Proctor, 61), Swailes, McIntosh, Hurst, Mullin (Barker, 53), Vernazza, Keane, Hoskins, Butler, Thorpe. Subs not used: Montgomery, Warne, Minto.
PNE line-up: Nash, Alexander, Mawene, Lucketti, Davidson, Sedgwick (Davis, 86), McKenna, O'Neil, Lewis (Hill, 67), Cresswell (Agyemang, 90), Nugent. Subs not used: Ward, Etuhu.
Attendance: 6,312
Referee: Mr A Penn (West Midlands)